Genetic variants in genes can influence phenotype
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I can explain how a genetic variant in a gene can influence an organism’s phenotype.
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When a mutation changes the sequence of nucleotide bases in a gene, this creates a genetic variant of the gene.
If a triplet code in a gene is changed, this may or may not change the amino acid sequence in the protein that is made.
A change in the amino acid sequence of a protein can change the 3D shape of the protein.
A change in the 3D shape of a protein can change what it does (e.g. by changing the shape of an enzyme’s active site).
These changes can have impacts on an organism’s phenotype.
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